Selected Publications |
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| SEARCH Pubmed for more publications | || Google Scholar Profile – H-index, i10-index and citations |
| Supervised Trainees are underlined |
2025
| R. Zhao, A. Wivagg, R.M. Lackner, J. Salsman, G. Dellaire, M.J. Matunis, D.M. Chenoweth, X. Zhao, H. Zhang (2025) “Telomeric SUMO level influences the choices of APB formation pathways and ALT efficiency.” BioRxiv preprint doi.org/10.1101/2025.01.16.633463 (LINK) |
| Price, D.W.J., F.S. Vizeacoumar, …. J. Salsman, D. Dahiya, C. Gonzalez-Lopez, P. Thibault, M. Levin, G. Dellaire, … A. Freywald, F.J. Vizeacoumar (2025) “Epigenetic Control of TERRA by FTSJ3 is Critical for Telomerase-Driven Cancers.” BioRxiv preprint doi.org/10.1101/2025.01.26.634101 (LINK) |
| Coyle, K.M., Y. Gao, R.E. Murphy, V. Martinez, A. Goodarzi, G. Dellaire, A. Wallace.(2025) “Multiple primary cancers in lung cancer patients in Atlantic Canada and implications for screening and management.” MedRxiv preprint doi.org/10.1101/2025.01.07.25320152 (LINK) |
| Thompson, J., F-M. Boisvert, J. Salsman, D. Lévesque, Graham Dellaire†, and N.D. Ridgway†.(2025) “The proximity interactome of PML isoforms I and II under fatty acid stress” FEBS Letters (in press)(†Co-corresponding authors) LINK |
2024
| Mathavarajah, S., E.B. Habib, W.D. Kim, M.M. Aoki, D.P. Corkery, K.I.T. Whelan, J. Lukacs, J. Salsman, Robert J. Huber, and G. Dellaire (2024) “The evolutionarily conserved PRP4K-CHMP4B/vps32 splicing circuit regulates autophagy” BioRxiv preprint doi.org/10.1101/2024.05.21.595022 (LINK) |
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Zhao R, M. Xu, A.R. Wondisford, R.M. Lackner,J. Salsman, G. Dellaire, D.M. Chenoweth, R.J. O’Sullivan, X. Zhao, H. Zhang (2024). “SUMO Promotes DNA Repair Protein Collaboration to Support Alterative Telomere Lengthening in the Absence of PML“. Genes Dev. 38(13-14):614-630 LINK
BioRxiv preprint 2024.02.29.582813 LINK |
| McPhee, M. J. Lee, J. Salsman, M. Pinelli, F. Di Cara, G. Dellaire, and N.D. Ridgway (2024). “Nuclear lipid droplets in CACO2 ells originate in situ at the nuclear envelope” Journal of Lipid Research 65(5):100540 (LINK) |
| Mathavarajah, S., A.W. Thomposon, M.R. Stoyek, T.A. Quinn, S. Roy, I. Braasch, and G. Dellaire (2024) “Suppressors of cGAS-STING are downregulated during finlimb regeneration and aging in aquatic vertebrates” J. Experimental Zoology (JEZ)-B Molecular and Developmental Evolution 342(3):241-251 – LINK |
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| Foster, J., M. McPhee, L. Yue, G. Dellaire, S. Pelech, and N.D. Ridgway (2024) “Lipid and phospho-regulation of CTP:Phosphocholine cytidylyltransferase-a association with nuclear lipid droplets” Molecular Biology of the Cell 35(3):ar33 LINK |
| Aoki, M.M., A.B. Kisiala, Mathavarajah, S., A. Schincagalia, J. Treverton, E. Habib, G. Dellaire, R.J.N. Emery, C.R. Brunetti, and R. Huber (2024) “From biosynthesis and beyond – Loss or overexpression of the cytokinin synthesis gene, iptA, alters cytokinesis and mitochondrial and amino acid metabolism in Dictyostelium discoideum” Faseb Journal 38:e23366 – LINK |
| Mathavarajah, S., and G. Dellaire (2024) “LINE-1: an emerging initiator of cGAS-STING signalling and inflammation that is dysregulated in disease” Biochemistry and Cell Biology 102(1):38-46 – LINK |
2023
| Mathavarajah, S., E.B. Habib, K.L. Vergunst, S.K. Williams, R. He, M. Maliougina, M. Park, J. Salsman, S. Roy, I. Braasch, A.J. Roger, D.N. Langelaan, and G. Dellaire (2023) “PML and PML-like exonucleases restrict retrotransposons in jawed vertebrates” Nucleic Acids Research 51(7):3185-3204 – LINK |
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| Dorighello, G., M. McPhee, K. Halliday, G. Dellaire, and N. Ridgway (2023) “Differential contributions of phosphotransferases CEPT1 and CHPT1 to phosphatidylcholine homeostasis and lipid droplet biogenesis.” Journal of Biological Chemistry 299(4):104578 – LINK |
| Suraweera, T.L., J.P.J. Merlin, G. Dellaire, Z. Xu, and H.P.V. Rupasinghe. (2023) “Genistein and Procyanidin B2 Reduce Carcinogen-Induced Reactive Oxygen Species and DNA Damage through the Activation of Nrf2/ARE Cell Signaling in Bronchial Epithelial Cells In Vitro.” International Journal of Molecular Science 24(4):3676. LINK |
2022
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Merlin, JPJ., S. Mathavarajah, G. Dellaire, KPJ. Murphy KPJ., and HPV. Rupasinghe (2002). “A Dietary Antioxidant Formulation Ameliorates DNA Damage Caused by gamma-Irradiation in Normal Human Bronchial Epithelial Cells In Vitro.” Antioxidants 11(7):1407 | Open Access |
Habib, EB, S. Mathavarajah, and G. Dellaire (2022) “Tinker, Tailor, Tumour Suppressor: The many functions of PRP4K” New Frontiers in Genetics 13: 839963 —>Open Access
| Mathavarajah, S., A. Melin, and G. Dellaire (2022) “SARS-CoV-2 and wastewater: What does it mean for non-human primates?” American J. Primatology 84(4-5):e23340.(Link)
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| Mcphee, KJ, J. Salsman, J. Foster, J. Thompson, S. Mathavarajah, G. Dellaire† and ND. Ridgway†(†Co-corresponding authors)(2022)”Running ‘LAPS’ around nLD: Nuclear lipid droplet form and function” Frontiers in Cell and Developmental Biology 10: 837406 —>Open Access |
| Salsman, J. and G. Dellaire (2022) “Super Resolution Radial Fluctuations (SRRF) Microscopy” In Methods in Molecular Biology: Fluorescence Microscopy, Bryan Heit (Ed), Springer Publisher’s Link | Archive Link |  |
| Kratzer, K., L. Getz, T. Pettrini, J-Y. Masson, and G. Dellaire (2022) “Addressing the dark matter of gene therapy: technical and ethical barriers to clinical application” Human Genetics 141(6):1175-1193 (SharedIt Link)
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2021
| Martinez-Pastor, B., GG. Silveira, TL. Clarke, D. Chung, Y.Gu, C. Cosentino, LS. Davidow, G. Mata, S. Hassanieh, J. Salsman, A. Ciccia, N. Bae, MT. Bedford, D. Megias, LL Rubin, A. Efeyan, G. Dellaire†, R. Mostoslavsky† (†Co-corresponding authors). (2021) “Assessing kinetics and recruitment of DNA repair factors using high content screens” Cell Reports 37(13): 110176 —> Open Access |
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| Clarke, L.E., A. Cook, S. Mathavarajah, A. Bera, J. Salsman, E. Habib, C. Van Iderstine, M. Bydoun, S.M. Lewis, and G. Dellaire (2021) “Haploinsufficient tumor suppressor PRP4K is negatively regulated during epithelial-to-mesenchymal transition” FASEB Journal (in press) —> Open Access
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| Merlin J. P.J. , G. Dellaire, K. Murphy, and H.P.V. Rupasinghe (2021) “Vitamin-Containing Antioxidant Formulation Reduces Carcinogen-Induced DNA Damage through ATR/Chk1 Signaling in Bronchial Epithelial Cells In Vitro” Biomedicines Open Access Link
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| Habib, E., A. Cook, S. Mathavarajah, and G. Dellaire (2021) “Adding some ‘Splice’ to Stress Eating: Autophagy, ESCRT and Alternative Splicing Orchestrate the Cellular Stress Response“ Genes 12(8):1196 (Link)
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| Cruickshank, B., M-C.D. Wasson, J.M. Brown, W. Fernando, J. Venkatesh, O.L. Walker, F. Morales-Quintanilla, M.L. Dahn, C.A. Dean, D. Vidovic, C. Van Iderstine, G. Dellaire, P. Marcato (2021) “LncRNA PART1 promotes survival, is associated with cancer stem cells, and alters the miRNA landscape in triple-negative breast cancer” Cancers 13(11):2644. (LINK) |
Merlin, J.P., H.P.V. Rupasinghe, G. Dellaire, and K. Murphy (2021) “Role of dietary antioxidants in p53-mediated cancer chemoprevention and tumor suppression” Oxid. Med. Cell. Longev. (LINK)
| Mathavarajah, S., C. Van Iderstine, G. Dellaire, and R.J. Huber (2021) “Cancer and the breakdown of multicellularity: What Dictyostelium discoideum, a social amoeba, can teach us” Bioessays 43(4):e2000156 – Journal Link, PDF
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| Mathavarajah, S., A.K. Stoddart, G.A. Gagnon, and G. Dellaire (2021) “Pandemic danger to the deep: the risk of marine mammals contracting SARS-CoV-2 from wastewater” Science of the Total Environment (STOTEN) 760:143346 LINK
BioRxiv (Preprint) NEWS COVERAGE: Fortune Magazine, Hakai Magazine,The Scientist, The Medical News |
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2020
| Mathavarajah, S., and G. Dellaire (2020) “Lions, tigers and kittens too: ACE2 and susceptibility to COVID-19” Evolution Medicine Public Health 2020(1):109-113 (LINK) |
| Lee J., J. Salsman, J. Foster, G. Dellaire*, N.D. Ridgway* (2020) “Lipid-associated PML structures assemble nuclear lipid droplets containing CCTα and Lipin” Life Science Alliance 3(8):e202000751. (LINK) BioRxiv. (Preprint) *Co-corresponding |
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| Tam, N., D Chung, SJ Baldwin, JR Simmons, L Xu, JK Rainey, G Dellaire, J. Frampton (2020) “Material properties of disulfide-crosslinked hyaluronic acid hydrogels influence prostate cancer cell growth and metabolism” Journal of Materials Chemistry B 8(42):9718-9733 (Abstract Link) |
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*Suraweera, T.L., H.P.V. Rupasinghe, G. Dellaire and Z. Xu (2020) “Regulation of Nrf2/ARE Pathway by Dietary Flavonoids: A Friend or Foe for Cancer Management?” Antioxidants 9(10), 973 (LINK) *Journal Cover |
| Getz, L. and G. Dellaire (2020) “Back to Basics: Application of the principles of bioethics to heritable genome interventions” Science and Engineering Ethics doi: 10.1007/s11948-020-00226-0. (LINK) (PDF) |
| Guisier F., M.C. Barros-Filho, L.D. Rock, M. Strachan-Whaley, E.A. Marshall, G. Dellaire, W.L. Lam (2020) “Janus or Hydra: The Many Faces of T Helper Cells in the Human Tumour Microenvironment.” Adv Exp Med Biol. 1224:35-51. doi: 10.1007/978-3-030-35723-8_3. (LINK) |
| Attwood, K., J. Salsman, D. Chung, S. Mathavarajah, C. Van Iderstine, G. Dellaire (2020) “PML isoform expression and DNA break location relative to PML nuclear bodies impacts the efficiency of homologous recombination” Biochemistry and Cell Biology 98(3):314-326(LINK)(PDF) |  |
| Beauchemin, H., P. Shooshtharizadeh, J. Pinder, G. Dellaire, and T. Moroy (2020) “Dominant negative Gfi1b mutations cause moderate thrombocytopenia and an impaired stress thrombopoiesis associated with mild erythropoietic abnormalities in mice” Haematologica 105(10):2457-2470 (LINK) |
| Pringle, E.S., J. Wertman, N. Melong, A.J. Coombs, A. Young, D. O’Leary, C. Veinotte, C. Robinson, M.N. Ha, G. Dellaire, T. Druley, C. McCormick, and J.N. Berman (2020) “The zebrafish xenograft platform – a novel tool for modeling KSHV-associated diseases” Viruses 12(1), 12 LINK |
| Rajan, V., N. Melong, W.H. Wong, B. King, R.S. Tong, N. Mahajan, D. Gaston, T. Lund, D. Rittenberg, G. Dellaire, C.J.V. Campbell, T. Druley, J.N. Berman (2020) “Humanized Zebrafish Enhance Human Hematopoietic Stem Cell Survival and Promote AML Clonal Diversity“Haematologica 105(10):2391-2399 (LINK) |
2019
| *Chung, D., J. Salsman, and G. Dellaire. (2019) “Inhibition of neddylation induces mitotic defects and alters MKLP1 accumulation at the midbody during cytokinesis” Cell Cycle 18(10):1135-1153 (LINK) *Journal Cover |
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| Darracq A, H. Pak, V. Bourgoin, F. Zmiri, G. Dellaire, E.B. Affar and E. Milot (2019) “NPM and NPM-MLF1 interact with chromatin remodeling complexes and influence their recruitment to specific genes.” PLoS Genetics 15(11):e1008463. (LINK) |
| Kofler, N., F. Baylis, G. Dellaire, and L. Getz (2019). “Genetically modifying mosquitoes to control the spread of disease carries unknown risks” – The Conversation.ca (LINK) |
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| Mathavarjah, S., J. Salsman and G. Dellaire (2019) “An emerging role for calcium signalling in innate and autoimmunity via the cGAS-STING axis“. Cytokine and Growth Factor Reviews 50:43-51 (LINK) |  |
| Rodrigue A, G. Margaillan, T. Torres Gomes, Y. Coulombe, G. Montalban, S. da Costa E Silva Carvalho, L. Milano L, M. Ducy, G. De-Gregoriis, G. Dellaire, W. Araújo da Silva Jr, AN. Monteiro, MA. Carvalho, J. Simard, JY. Masson (2019) “A global functional analysis of missense mutations reveals two major hotspots in the PALB2 tumor suppressor.“. Nucl. Acids Res. 47(20):10662-10677 (LINK) |
| Deveryshetty, J., M. Ryzhikov1, N. Brahiti, T. Peterlini, G. Dellaire, J-Y. Masson and S. Korolev (2019) “Novel strand exchange activity of the human PALB2 DNA Binding Domain and its critical role for DNA repair in cells” Elife (LINK) BioRxiv |
| Getz, L. and G. Dellaire (2019). “Moratorium on Human Genome Editing: Time to Get It Right” – The Hastings Center Bioethics Forum Essay (LINK)  |
| Martinez, V.D., A.P. Sage, E.A. Marshall, M. Suzuki, A.A. Goodarzi, G. Dellaire and W.L. Lam (2019) “Oncogenetics of lung cancer induced by environmental carcinogens“. Chapter in Oncogenes and Carcinogenesis @IntechOpen (LINK) |
| Getz, L. and G. Dellaire (2019). “CRISPR gene editing: Why we need Slow Science” – The Conversation.ca (LINK)  |
| Martin, L.T.P., M.W. Nachtigal, T. Selman, E. Nguyen, J. Salsman, G. Dellaire, and D.J. Dupré (2019) “Bitter taste receptors are expressed in human epithelial ovarian and prostate cancers and impact cell survival“. Molecular and Cellular Biochemistry 454(1-2):203-214 (LINK) |
2018
| Corkery, D., L. Clarke, S. Gebremeskel, J. Salsman, J. Pinder, C. Le Page, Z. Xu, Anne-Marie Mes-Masson, B. Johnston, J.N. Berman, and G. Dellaire (2018) “Loss of PRP4K drives anoikis resistance in part by dysregulation of epidermal growth factor receptor endosomal trafficking” Oncogene 37(2):174-184 (LINK) |
| Baranes-Bachar K, Levy-Barda A, Oehler J, Reid DA, Soria-Bretones I, Voss TC, Chung D, Park Y, Liu C, Yoon JB, Li W, Dellaire G, Misteli T, Huertas P, Rothenberg E, Ramadan K, Ziv Y, Shiloh Y. (2018) “The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation at Sites of DNA Damage, Facilitating Double-Strand Break Repair“. Mol Cell. 69(5):866-878.e7. (LINK) |
| Getz, L., G. Dellaire, and F. Baylis (2018). “Why we are not ready for genetically designed babies.” – The Conversation.ca (LINK)  |
| Castroviejo-Bermejo, M., C. Cruz, A. Llop-Guevara, S. Gutiérrez-Enríquez, M. Ducy, Y. Ibrahim, A. Gris-Oliver, A. Bruna, M. Guzmán, O. Rodriguez, J. Grueso, S. Bonache, A. Moles-Fernández, C. Viaplana, P. Gómez-Pardo, M. Vidal, V. Peg, X. Serres-Créixams, G. Dellaire, J. Simard, P. Nuciforo, I. Rubio, R. Dienstmann, C.J. Barret, C. Caldas, J. Baselga, C. Saura, J. Cortés, O. Déas, J. Jonkers, J-Y. Masson, S. Cairo, J-G. Judde, M. O’Connor, O. Díez, J. Balmaña, and V. Serra (2018) “RAD51 score identifies homologous recombination repair deficient tumors with PARP inhibitor sensitivity and is feasible in routine clinical samples of breast cancer”. EMBO Molecular Medicine pii. e9172. ( LINK ) |
| Getz, L. and Dellaire G. (2018) “Angels and Devils: Dilemmas in Dual-Use Biotechnology“. Trends in Biotechnology. (LINK) |
| Getz, L., G. Dellaire, and F. Baylis (2018). “Jiankui He: A Sorry tale of High-Stakes Science” – The Hastings Center Bioethics Forum Essay (LINK)  |
| Stairs CW, Eme L, Muñoz-Gómez S, Cohen A, Dellaire G, Shepherd JN, Fawcett JP, Roger AJ. (2018) “Microbial eukaryotes have adapted to hypoxia by horizontal acquisitions of a gene involved in rhodoquinone biosynthesis“. Elife 7. pii: e34292. (LINK) |
| Sage AP, Martinez VD, Minatel BC, Pewarchuk ME, Marshall EA, MacAulay GM, Hubaux R, Pearson DD, Goodarzi AA, Dellaire G, Lam WL.(2018) “Genomics and Epigenetics of Malignant Mesothelioma“. High Throughput. 7(3). (LINK) |
| Vadnais C, Chen R, Fraszczak J, Yu Z, Boulais J, Pinder J, Frank D, Khandanpour C, Hébert J, Dellaire G, Côté JF, Richard S, Orthwein A, Drobetsky E, Möröy T. (2018) “GFI1 facilitates efficient DNA repair by regulating PRMT1 dependent methylation of MRE11 and 53BP1“. Nat Commun. 9(1):1418. (LINK) |
| George V.C., S. Ansari, V.S. Chelakkot, A.L. Chelakkot, C. Chelakkot, V. Menon, W. Ramadan, K.R. Ethiraj, R. El-Awady, T. Mantso, M. Mitsiogianni, M.I. Panayiotidis, G. Dellaire, and H.P.V. Rupasingh (2018) “DNA-dependent protein kinase: Epigenetic alterations and the role in genomic stability of cancer“. Mutation Research 3(3):130-8 (LINK) |
2017
| Melong, N, Steele S, MacDonald M, Holly A, Collins CC, Zoubeidi A, Berman JN, and Dellaire G (2017)“Enzalutamide inhibits testosterone-induced growth of human prostate cancer xenografts in zebrafish and can induce bradycardia”, Scientific Reports 7(1):14698. (LINK)Dalhousie News Story on our Findings via Dal News | 
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| Gebremeskel S, Lobert L, Tanner K, Walker B, Oliphant T, Clarke LE, Dellaire G, Johnston B.(2017) “Natural killer T-cell immunotherapy in combination with chemotherapy-induced immunogenic cell death targets metastatic breast cancer.” Cancer Immunology Research . 5(12):1086-1097 (LINK) |
| Lobbardi R, Pinder J, Martinez-Pastor B, Theodorou M, Blackburn JS, Abraham BJ, Namiki Y, Mansour M, Abdelfattah NS, Molodtsov A, Alexe G, Toiber D, de Waard M, Jain E, Boukhali M, Lion M, Bhere D, Shah K, Gutierrez A, Stegmaier K, Silverman LB, Sadreyev RI, Asara JM, Oettinger MA, Haas W, Look AT, Young RA, Mostoslavsky R, Dellaire G, Langenau DM. (2017) “TOX regulates growth, DNA repair, and genomic instability in T-cell Acute Lymphoblastic Leukemia” Cancer Discovery. 7(11):1336-1353. (LINK) |
 Technology Networks News story on this article |
| Dellaire G. (2017) “Editorial: CRISPR Medicine: From Bench to Bedside.” Curr Gene Therapy 17(4):261-262. (LINK) doi: 10.2174/156652321704180104153508.
Salsman J, Masson JY, Orthwein A, Dellaire G. (2017)”CRISPR/Cas9 Gene Editing: From Basic Mechanisms to Improved Strategies for Enhanced Genome Engineering In Vivo.” Curr Gene Therapy 17(4):263-274. (PDF) doi: 10.2174/1566523217666171122094629. |
| George VC, Dellaire G, Rupasinghe HPV.2017 “Plant flavonoids in cancer chemoprevention: role in genome stability.” J Nutr Biochem. 45:1-14. (LINK) |
| Salsman J, Rapkin LM, Margam NN, Duncan R, Bazett-Jones DP, and G. Dellaire (2017) “Myogenic differentiation triggers PML nuclear body loss and DAXX relocalization to chromocentres.” Cell Death & Disease 8(3):e2724 (LINK) |  |
| Salsman, J. and Dellaire G (2017) “Precision genome editing in the CRISPR era. ” Biochemistry and Cell Biology. 95(2):187-201 (PDF LINK) |
| Agudelo D, Duringer A, Bozoyan L, Huard CC, Carter S, Loehr J, Synodinou D, Drouin M, Salsman J, Dellaire G, Laganière J, Doyon Y.(2017) “Marker-free coselection for CRISPR-driven genome editing in human cells.” Nature Methods 14(6):615-620 (LINK) |  |
| Salsman J, Stathakis A, Parker E, Chung D, Anthes LE, Koskowich KL, Lahsaee S, Gaston D, Kukurba KR, Smith KS, Chute IC, Léger D, Frost LD, Montgomery SB, Lewis SM, Eskiw C, and G. Dellaire (2017) “PML nuclear bodies contribute to the basal expression of the mTOR inhibitor DDIT4.” Scientific Reports 7:45038 (LINK) |  |
| Buisson, R., N. Joshi, A. Rodrigue, C.K. Ho, J. Kreuzer, T.K. Foo, E.J.-L. Hardy, G. Dellaire, W. Haas, B. Xia, J.-Y. Masson, and L. Zou. (2017) “Coupling of Homologous Recombination and the Checkpoint by ATR” Mol. Cell 65(2):336-346 (LINK) |
| Ramdzan, Z.M., V. Ginjala, J.B. Pinder,D. Chung, C.M. Donovan, S. Kaur, L. Leduy, G. Dellaire, S. Ganesan, and A. Nepveu. (2017) “The DNA Repair Function of CUX1 Contributes to Radioresistance” Oncotarget 8(12):19021-19038 (LINK) |
| Pauty, J., A. Couturier,A. Rodrigue, M. Caron, Y. Coulombe. G. Dellaire and J.-Y. Masson (2017) “Cancer-causing mutations in the tumour suppressor PALB2 reveals a novel cancer mechanism using hidden nuclear export signal in the WD40 repeat motif”. Nucl. Acids Res. 45(5):2644-2657 |
2016
| Couturier, A., H. Fleury, A-M. Patenaude, V. Bentley, Y. Coulombe, A. Rodrigue, N. Joshi, J. Pauty, J. Berman, G. Dellaire, J. di Noia, A-M. Mes-Masson, and J-Y. Masson. (2016) “Functions for APRIN (PDS5B) in homologous recombination and in ovarian cancer prediction”. Nucl. Acids Res. 44(22):10879-10897(LINK) |
| George, V.C., G. Dellaire, and H.P. Rupasinghe (2016) “Plant flavonoids in cancer chemoprevention: role in genome stability“. J Nutr Biochem. 45:1-14 (LINK) |
| Kahn, I., B. Yoo, O. Masson, S. Baron, D. Corkery, G. Dellaire, L. Attardi, and K. Rosen. (2016) “ErbB2-dependent downregulation of a pro-apoptotic protein Perp is required for oncogenic transformation of breast epithelial cells”. Oncogene 35(44):5759-5769 (LINK) |
| The Functional Nucleus Editors: David J. Bazett-Jones, Graham Dellaire. Springer DE Available from Amazon.com (LINK)  |
| Lahsaee S, D.P. Corkery, L.E. Anthes, A. Holly, J. Salsman, and G. Dellaire. (2016) “Estrogen receptor alpha (ESR1)-signalling regulates the expression of the taxane-response biomarker PRP4K.” Experimental Cell Research 340(1):125-31 ( LINK ) |
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| Wertman, J., C.J. Veinotte, G. Dellaire, J.N. Berman. (2016) “The Zebrafish Xenograft Platform: Evolution of a Novel Cancer Model and Preclinical Screening Tool”. Adv Exp Med Biol 916:289-314 ( LINK ) |
| Rajan, V., G. Dellaire, and J.N. Berman. (2016) “Modeling Leukemogenesis in the Zebrafish Using” Genetic and Xenograft Models. Methods Mol Biol. 1451:171-89 ( LINK ) |
2015
| Pinder, J., J. Salsman, and G. Dellaire. (2015). “Nuclear domain “knock-in” screen for the evaluation and identification of small molecule enhancers of CRISPR-based genome editing” Nucleic Acids Research doi: 10.1093/nar/gkv993 (LINK) |  |
| Corkery, D.C., C. Le Page, L. Meunier, D. Provencher, A-M. Mes-Masson G. Dellaire (2015) “PRP4K, a HER2 regulated modifier of taxane sensitivity” Cell Cycle 14(7):1059-69 (LINK) |
| Chung, D., and G. Dellaire (2015) “The Role of the COP9 Signalosome and Neddylation in DNA Damage Signaling and Repair” Biomolecules 5(4): 2388-2416 (LINK) |
| Corkery, D., A. Holly, S. Lahsaee, and G. Dellaire. (2015). “Connecting the Speckles: Splicing kinases and their role in tumorigenesis and treatment response” Nucleus 6(4):279-88 (LINK) |
| El-Naggar, A.M., C.J Veinotte, H. Cheng, T.G.P. Grunewald, G. Luca Negri, S. Prakash Somasekharan, D.P. Corkery, F. Tirode, J. Mathers, D. Khan, A.H Kyle, J.H Baker, N.E. LePard, S.McKinney, S.Hajee, M. Bosiljcic, G. Leprivier, C.E. Tognon, A.I. Minchinton, K.L. Bennewith, O.Delattre, Y. Wang, G. Dellaire, J.N. Berman, and P.H. Sorensen. (2015) “Translational activation of HIF1a by YB-1 promotes sarcoma metastasis“. Cancer Cell 27(5):682-97 (LINK) |
| Kalousi, A., A-S. Hoffbeck, P. Selemenakis, J. Pinder, K.I. Savage, K.K. Khanna, L. Brino, G. Dellaire, V.G. Gorgoulis, and E. Soutoglou (2015) “The nuclear oncogene SET controls DNA repair by KAP1 and HP1 retention on chromatin”. Cell Reports pii: S2211-1247(15)00257-0 (LINK) |
| Sidik S., J. Salsman, G. Dellaire, and J. Rohde (2015) “Shigella infection interferes with SUMOylation and increases PML-NB number”. PLoS ONE 10(4):e0122585 (LINK) |
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Bentley V.L., C.J. Veinotte, D.P. Corkery, J.B. Pinder, M.A. LeBlanc, K. Bedard, A.P. Weng, J.N. Berman, and G. Dellaire. (2015) “Focused chemical genomics using zebrafish xenotransplantation as a pre-clinical therapeutic platform for T-cell acute lymphoblastic leukemia.” Haematologica 100(1):70-6. (LINK) |
| Cancer Genomics: From Bench to Personalized Medicine. Editors: G. Dellaire, J.N. Berman and R. Arceci. Elsevier (LINK) |
 Available from Amazon.ca |
2014
| Stairs, C.W., L. Eme, L., M.W. Brown, C. Mutsaers, E. Susko, G. Dellaire, D. Soanes, M. van der Giezen, and A.J. Roger (2014) “A mitochondrial sulfur mobilization (SUF) system in the anaerobe Pygsuia”. Current Biology 24(11):1176-86 |
| Veinotte, C, G. Dellaire, and J. N. Berman (2014) “Hooking the Big One: The potential of zebrafish xenotransplantation to reform cancer drug screening in the genomic era” Disease Models and Mechanisms. (7):745-754 |
| Liu, Y., A. Asnani, L. Zou, V.L. Bentley, M. Yu, Y. Wang, G. Dellaire, K.S. Sarkar, M. Dai, H.H. Chen, D.E. Sosnovik, J.T. Shin, D.A. Haber, J.N. Berman, W. Chao, R.T. Peterson. (2014) “Visnagin protects against doxorubicin-induced cardiomyopathy through modulation of mitochondrial malate dehydrogenase.” Science Trans. Med. 6(266):266ra170 (LINK)
Klement, K., M.S. Luijsterburg, J.B. Pinder, C.S. Cena, V. Del Nero, C.M. Wintersinger, G. Dellaire, H. van Attikum, A.A. Goodarzi. (2014) “Opposing ISWI- and CHD-class chromatin remodeling activities orchestrate heterochromatic DNA repair.” J. Cell Biol. 207(6):717-733 (LINK)
Lemaître, C., A. Grabarz, K. Tsouroula, L. Andronov, A. Furst, T. Pankotai, V. Heyer, M. Rogier, K.M. Attwood, P. Kessler, G. Dellaire, B. Klaholz, B. Reina-San-Martin, and E. Soutoglou. (2014) “Nuclear position dictates DNA repair pathway choice.” Genes Dev. 28(22):2450-63 (LINK) |
2013
| Smithen DA, Forrester AM, Corkery DP, Dellaire G, Colpitts J, McFarland SA, Berman JN, Thompson A. (2013) “Investigations regarding the utility of prodigiosenes to treat leukemia.“.Org Biomol Chem. 11(1):62-8 (LINK) |  |
| Langelaan DN, Reddy T, Banks AW, Dellaire G, Dupré DJ, Rainey JK. (2013) “Structural features of the apelin receptor N-terminal tail and first transmembrane segment implicated in ligand binding and receptor trafficking“. Biochim Biophys Acta. 1828(6):1471-83 (LINK) |
| Salsman J, J. Pinder, B. Tse, D. Corkery, G. Dellaire. (2013) “The translation initiation factor 3 subunit eIF3K interacts with PML and associates with PML nuclear bodies“. Exp Cell Res. 319(17):2554-65.(LINK) (PDF) |
| Pinder JB, Attwood KM, and Dellaire G..(2013) “Reading, writing, and repair: the role of ubiquitin and the ubiquitin-like proteins in DNA damage signaling and repair.” Front Genet. 4:45 (LINK) |
| Hawco CLA, Marchal E, Uddin I, Baker AEG, Corkery DP, *Dellaire G and *Thompson A.(2013) “Synthesis and biological evaluation of prodigiosene conjugates of porphyrin, estrone and 4-hydroxytamoxifen.” Bioorganic & Med. Chem. 21(19):5995-6002 (LINK) *Co-corresponding |
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| Soares IN, Caetano FA, Pinder J, Roz Rodrigues B, Beraldo FH, Ostapchenko VG, Durette C, Schenatto Pereira G, Lopes MH, Queiroz-Hazarbassanov N, Cunha IW, Sanematsu PI, Suzuki S, Bleggi-Torres LF, Schild-Poulter C, Thibault P, Dellaire G, Martins VR, Prado VF, Prado MA. (2013) “Regulation of stress-inducible phosphoprotein 1 nuclear retention by PIAS1” Mol Cell Proteomics. 12(11):3253-70 (LINK) |
2012
Konantz M, Balci TB, Hartwig UF, Dellaire G, André MC, Berman JN, Lengerke C. (2012)
“Zebrafish xenografts as a tool for in vivo studies on human cancer.” Ann N Y Acad Sci. 2012 1266:124-37(LINK)
| Andrin, C., D. McDonald, K.M. Attwood, A. Rodrigue, S. Ghosh, R. Mirzayans, J-Y. Masson, G. Dellaire, and M.J. Hendzel (2012) “A Requirement for polymerized actin in DNA double strand break repair.“Nucleus 2012 3(4) (LINK) |
| Kuang, Y-Q., N. Charette, J. Frazer, P.J. Holland, K.M. Attwood, G. Dellaire, D.J. Dupré. (2012) “Dopamine Receptor-Interacting Protein 78 Acts as a Molecular Chaperone for CCR5 Chemokine Receptor Signaling Complex Organization“. PLos ONE 7(7): e40522 (LINK) |
| *Salsman, J., M. Jagannathan, P. Paladino, P.-K. Chan, G. Dellaire, B. Raught, and L. Frappier (2012) “Proteomic profiling of the human cytomegalovirus UL35 gene products reveals a role for UL35 in the DNA repair response ” Journal of Virology 86(2):806-20 (LINK) *Cover of JVI issue 86(4)  |
2011
| Xavier, A.C., H. Edwards, A.A. Dombkowski, T.B. Balci, J.N. Berman, G. Dellaire, C. Xie, S.A. Buck, L.H. Matherly, Y. Ge, and J.W. Taub. (2011) “A unique role for GATA1 in Down Syndrome acute megakaryocytic leukemia biology and therapy” PLoS ONE 6(11): e27486. (LINK) |
| Bauer, D.C., K. Willadsen, F.A. Buske, K. LeCao, T.L. Bailey, G. Dellaire, and M. Bodén. (2011) “Sorting the nuclear proteome” Bioinformatics 27(13):i7-14 (LINK) |
| Corkery, D., G. Dellaire*, and J. Berman (2011) “Leukemia Xenotransplantation in Zebrafish – Chemotherapy Response Assay in vivo” British Journal of Haematology 153(6):786-789 * Joint corresponding author LINK |
| *Kepkay, R., K.M. Attwood, Y. Ziv, Y., Shiloh, and G. Dellaire (2011) “KAP1 depletion increases PML nuclear body number in concert with ultrastructural changes in chromatin.” Cell Cycle 10(2):308-322 PDF *This article was also the subject of two News & Views articles: Hemmerich, 2011; Salomoni, 2011 |
| Cann, K. and G. Dellaire (2011) “Heterochromatin and the DNA damage response: the need to relax” Biochem. Cell Biol. 89(1):45-60 LINK |
| Cann, K., S. Huang and G. Dellaire (2011) “ Nuclear Subdomains in Cancer“, book chapter In Advances in Nuclear Architecture, Eds. Adams and Freemont, Springer. |
2010
| Bodén M., G. Dellaire, K. Burrage, T.L. Bailey (2010) “A Bayesian network model of proteins’ association with promyelocytic leukemia (PML) nuclear bodies.” J. Comput. Biol. 17(4):617-630
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2009
| *Dellaire, G., R. Kepkay and D.P.Bazett-Jones (2009) “High resolution imaging of changes in the structure and spatial organization of chromatin, γ-H2A.X and the MRN complex within etoposide-induced DNA repair foci.“. Cell Cycle. 8(22):3750-3769 *(Cover of Cell Cycle) LINK
This article was also subject of a News & Views article. |
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2007
| Dellaire, G. and D.P.Bazett-Jones (2007) “Beyond Repair Foci: Subnuclear Domains and the Cellular Response to DNA Damage“. Cell Cycle. 6(15):1864-1872. LINK |
2006
| Dellaire, G., R. Ching, K. Ahmed, K. Tse, F. Jalali, R.G. Bristow, and D.P. Bazett-Jones. (2006a) “PML nuclear bodies are DNA damage sensors whose response to DNA double-strand breaks is regulated by NBS1, Chk2 and ATR”.J.Cell Biol. 175(1):55-66 LINK |
| Block, G., C.H. Eskiw, G. Dellaire, and D.P. Bazett-Jones.(2006) “Transcriptional regulation is affected by subnuclear targeting of reporter plasmids to PML nuclear bodies” Mol. Cell. Biol. 26(23):8814-8825 LINK |
| *Dellaire, G., R. Ching, H. Dehghani, Y. Ren and D.P. Bazett-Jones. (2006b) “ PML nuclear bodies increase in number in early S-phase by a fission mechanism”. J. Cell Sci. 119(6):1026-1033. (*article highlighted by JCS). LINK |
| *Dellaire, G., C. Eskiw, H. Dehghani, R. Ching, and D.P. Bazett-Jones. (2006c) “Mitotic Accumulations of PML protein (MAPPs) contribute to the post-mitotic re-establishment of PML nuclear bodies.” J. Cell Sci. 119(6):1034-1042. (*article highlighted by JCS).LINK |
| *Kruhlak, M.J.,A. Celeste, G. Dellaire, O. Fernandez-Capetillo,W.G. Müller, J.G. McNally, D.P. Bazett-Jones, and A. Nussenzweig. (2006) “Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks” J. Cell Biol. 172(6):823-834 (*Highlighted by JCB, reviewed by the Faculty of 1000) LINK |
2005
| Dehghani, H., G.Dellaire, and D.P. Bazett-Jones (2005) “Organisation of chromatin in the interphase mammalian cell”. Micron 36(2):95-108. Pubmed |
| *Al Rashid, S.T., G. Dellaire, F. Jalali, M. Vaid, M. Folkard, Y. Xu, D.J. Chen,L. Lilge,K.M. Prise, D.P. Bazett-Jones, and R.G. Bristow. (2005) “Evidence for the direct binding of phosphorylated p53 to sites of DNA breaks In vivo. “ Cancer Res. 65(23):10810-10821 *(Cover of Cancer Res.) Pubmed |
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| Ching, R.W., G. Dellaire, C.H. Eskiw and D.P. Bazett-Jones (2005) “PML nuclear bodies: a meeting place for genomic loci?” J. Cell Sci. 118(5):847-854. Pubmed |
2004
| *Dellaire, G. and D.P. Bazett-Jones (2004) “PML nuclear bodies: Dynamic sensors of DNA damage and cellular stress”. Bioessays 26(9):963-977. *(Cover of Bioessays)LINK |
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2003
| *Eskiw, C., G. Dellaire, J.S. Mymryck and D.P. Bazett-Jones. (2003)“Size, position and dynamic behaviour of PML nuclear bodies following cell stress as a paradigm for supramolecular trafficking and assembly”J. Cell Sci. 116(21): 4455-4466. *(article highlighted by JCS, cover caption). Pubmed | |
| *Dellaire, G., R. Farrall, and W.A. Bickmore. (2003) “The Nuclear Protein Database (NPD): Subnuclear localization and functional annotation of the nuclear proteome”. Nucl. Acids Res 31(1):328-330. | |
| *(reviewed by Nat. Rev. Genet., J. Cell Sci. and Science) Pubmed | Visit NPD! |
2002
*Dellaire, G., J. Yan, K. Little, R. Drouin and P. Chartrand. (2002b) “Evidence that extrachromosomal and chromosomal double-strand break repair are coupled in mammalian cells”. Chromosoma 111(5):304-312. *(Cover of Chromosoma) Free LINK |
Collins, N., Garcia-Jimenez, N., I. Kukimoto, C. Garcia-Jimenez, G.Dellaire, and P. D. Varga-Weisz (2002) “ACF1 chromatin remodeling factor is essential for DNA replication in mammalian cells.” Nat. Genet. 32(4):627-632. Pubmed
Dellaire, G., E. M. Makarov, J.J. Cowger, D. Longman, H.G.E. Sutherland, R. Luhrmann, J. Torchia and W.A. Bickmore. (2002a) “Mammalian PRP4 kinase copurifies and interacts with components of both the U5 snRNP and the N-CoR deacetylase complexes”. Mol. Cell. Biol. 22(14):5141-5156. Free LINK
Ladomery, M., and G. Dellaire. (2002) “Multifunctional zinc finger proteins in development and disease” Ann Hum Genet. 66(Pt 5-6):331-42 Pubmed
2001
Sutherland, H.G., Mumford, G.K., Newton, K., Ford, L.V., Farrall, R., Dellaire, G., Caceres, J.F., Bickmore, W.A. “Large-scale identification of mammalian proteins localized to nuclear sub-compartments.”Hum Mol Genet. 2001 Sep 1;10(18):1995-2011. Pubmed
2000
| Poot, R.A., Dellaire, G., Hulsmann, B.B., Grimaldi, M.A., Corona, D.F., Becker, P.B., Bickmore, W.A., and Varga-Weisz, P.D. (2000) “HuCHRAC, a human ISWI chromatin remodelling complex contains hACF1 and two novel histone-fold proteins.”EMBO J. 2000 Jul 3;19(13):3377-3387. Pubmed |
1999
| *Dellaire, G., and P. Chartrand. (1999) “Direct evidence that transgene integration is random in murine cells, implying that naturally occurring double-strand breaks may be distributed similarly within the genome.”Radiation Research 149(4):325-9.1997. JSTOR LINK |
1997
| Dellaire, G., Lemieux N, Belmaaza A,and P. Chartrand. (1997) “Ectopic gene targeting exhibits a bimodal distribution of integration in murine cells, indicating that both intra- and interchromosomal sites are accessible to the targeting vector.”Molecular and Cellular Biology 17(9):5571-80. LINK |
Dellaire Laboratory | Dalhousie University | Tel: (902)494-4730 | Fax: (902)494-2519