GRADUATE POSITION IN DNA REPAIR/CANCER BIOLOGY
AT DALHOUSIE UNIVERISTY

PROJECT TITLE: To study the role of ubiquitin-like proteins in DNA repair

START DATE: Sept. 2016

PROJECT DESCRIPTION:
DNA damage has the potential to create mutations in our genes that increase an individual’s chances of developing cancer. Therefore, a key question in cancer biology is how the cell detects and repairs DNA damage? Our laboratory at Dalhousie University in Halifax, Nova Scotia, studies nuclear structure and function in vertebrates with a focus on DNA repair mechanisms and their role in tumour suppression. Research projects are available for an M.Sc. or Ph.D. candidate to study how ubiquitin-like modifiers regulate DNA repair in mammalian cells and in the zebrafish. More information on the Dellaire laboratory and on-going projects can be obtained from our website: dellairelab.medicine.dal.ca

FUNDING: Natural Sciences and Engineering Research Council (NSERC) (2015-2020)

SKILLS TO BE ACQUIRED:
• mammalian tissue culture
• cell transfection and DNA damage assays
• bacterial protein expression and yeast-two hybrid assays
• protein-protein interaction assays
• multiplex mass spectrometry analysis of protein expression and modification
• spinning-disk and light-sheet live-cell microscopy
• zebrafish animal handling, genetic manipulation, and microinjection
• CRISPR-mediated genome engineering

HOW TO APPLY
To apply for this position, please provide the following
1) Your most recent transcripts (unofficial),
2) Your CV, including at least 2 academic/research references
3) A brief statement describing your research interests and career goals

Preference will be given to Canadian (or landed immigrant) students with previous research experience and a GPA of 3.7/4.0 or higher who would be eligible for Alexander Graham Bell or Vanier NSERC studentship funding.
See: NSERC Studentship INFO deadline December 1, 2015

Send these materials by mail or e-mail to:

Dr. Graham Dellaire
Depts. of Pathology and Biochemistry & Molecular Biology, Dalhousie University
P.O. BOX 15000
Halifax, Nova Scotia, Canada, B3H 4R2
Tel: (902)494-4730
Fax: (902)494-2519
E-mail: dellaire (at) dal.ca

ABOUT DALHOUSIE UNIVERSITY
Located in the heart of Halifax, Nova Scotia, Dalhousie is a leading, research-intensive Canadian university offering more than 180 degree programs in 11 diverse faculties and attracting over $132 million in research grants and awards each year. In particular, Dalhousie University has a vibrant and nationally recognized Cancer Research Training Program (CRTP) funded by the Canadian Institutes of Health Research and the Terry Fox Research Institute. Established in 1818, Dalhousie is also one of the oldest universities in Canada. Come be a part of history and consider joining Dalhousie University for graduate studies.